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What stimulates hemoglobin production? In order to make red blood cells, the body maintains an adequate supply of erythropoietin (EPO), a hormone that is produced by the kidney. Having more red blood cells raises your hemoglobin levels. Hemoglobin is the protein in red blood cells that helps blood carry oxygen throughout the body. Is there a generic for Epogen? No, there is not a generic version of Epogen (epoetin alfa) available. The patent for this drug expired in 2013. However, this drug is considered a biologic (a drug created by a biological process rather than a chemical process). A biosimilar of Epogen, called Retacrit, has been submitted for FDA approval. What is the role of erythropoietin? The role of erythropoietin is to control red blood cell production by regulating the differentiation and proliferation of erythroid progenitor cells in the bone marrow. Produced primarily in the kidney, erythropoietin circulates in the plasma and acts on target cells in the bone marrow.
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